Adenosine 5′-monophosphate | 61-19-8 : kuv

Adenosine 5'-monophosphate (AMP) yog ib qho nucleotide tsim los ntawm adenine, ribose, thiab ib pawg phosphate.

Chemical Structure: AMP yog muab los ntawm nucleoside adenosine, qhov twg adenine txuas rau ribose, thiab ib pab pawg phosphate ntxiv yog txuas rau 5 'carbon ntawm ribose los ntawm phosphoester daim ntawv cog lus.

Lub luag haujlwm lom neeg: AMP yog ib qho tseem ceeb ntawm nucleic acids, ua haujlwm ua monomer hauv kev tsim kho ntawm RNA molecules. Hauv RNA, AMP tau muab tso rau hauv cov saw hlau polymer los ntawm phosphodiester bonds, tsim cov pob txha ntawm RNA strand.

Zog Metabolism: AMP tseem koom nrog hauv cellular zog metabolism. Nws ua haujlwm ua ntej rau adenosine diphosphate (ADP) thiab adenosine triphosphate (ATP) los ntawm cov tshuaj tiv thaiv phosphorylation catalyzed los ntawm enzymes xws li adenylate kinase. ATP, tshwj xeeb, yog lub luag haujlwm tseem ceeb hauv cov hlwb, muab lub zog rau ntau yam txheej txheem ntawm tes.

Txoj Cai Metabolic: AMP ua lub luag haujlwm hauv kev tswj hwm lub zog ntawm tes. Cellular AMP theem tuaj yeem hloov pauv hauv cov lus teb rau kev hloov pauv hauv metabolic thiab xav tau lub zog. Cov qib siab ntawm AMP txheeb ze rau ATP tuaj yeem ua kom muaj zog ntawm tes-sensing txoj hauv kev, xws li AMP-activated protein kinase (AMPK), uas tswj cov metabolism kom tswj tau lub zog homeostasis.

Kev noj haus: AMP tuaj yeem tau txais los ntawm cov khoom noj khoom haus, tshwj xeeb tshaj yog nyob rau hauv cov khoom noj uas muaj nucleic acids, xws li nqaij, ntses, thiab legumes.

Pharmacological Applications: AMP thiab nws cov derivatives tau tshawb xyuas rau cov kev siv tshuaj kho mob. Piv txwv li, cAMP (cyclic AMP), ib tug derivative ntawm AMP, ua hauj lwm raws li ib tug thib ob messenger nyob rau hauv lub teeb liab transduction txoj kev thiab yog tsom los ntawm ntau yam tshuaj rau kev kho mob ntawm cov mob xws li mob hawb pob, mob plawv, thiab hormonal imbalances.