Huperzine A ｜120786-18-7
Product Description:
Huperzine A yog ib qho kev paub txog kev txawj ntse uas inhibits enzymes uas degrade cov kev kawm neurotransmitter acetylcholine. Nws yog nyob rau hauv chav kawm cholinergic ntawm cov molecules uas yuav pab tiv thaiv kev paub tsis meej ntawm cov neeg laus.
Huperzine A yog ib qho chaw muab rho tawm los ntawm tsev neeg huperzine. Nws yog hu ua acetylcholinesterase inhibitor, uas txhais tau hais tias nws tiv thaiv cov enzyme los ntawm kev rhuav tshem acetylcholine, ua rau muaj kev nce hauv acetylcholine.
Acetylcholine yog hu ua kev kawm neurotransmitter thiab tseem koom nrog hauv cov leeg nqaij.
Huperzine A zoo li yog ib qho chaw muaj kev nyab xeeb. Toxicity thiab tib neeg kev tshawb fawb los ntawm kev tshawb fawb tsiaj tau pom tias tsis muaj kev phiv ntawm cov tshuaj ntxiv. Huperzine A kuj tau siv rau hauv kev sim ua ntej los tiv thaiv Alzheimer's disease.
Huperzine A tshwm sim hauv cov kua cerebrospinal thiab yooj yim hla cov ntshav-hlwb barrier.
Huperzine A yog qhov zoo tshaj plaws hu ua acetylcholinesterase inhibitor. Hauv particular, nws inhibits G4 subtype ntawm acetylcholinesterase, uas yog ib txwm muaj nyob rau hauv cov tsiaj lub hlwb. Nws muaj txiaj ntsig zoo dua lossis sib npaug ntawm lwm cov acetylcholinesterase inhibitors, xws li tacillin lossis rivastatin. Raws li ib qho inhibitor, nws muaj kev sib raug zoo rau acetylcholinesterase. Nyob rau tib lub sij hawm, nws muaj ib tug qeeb dissociation tas li, uas ua rau nws ib nrab-lub neej ntev heev.
Ntxiv nrog rau inhibiting acetylcholinesterase, nws tseem tuaj yeem pom tias yog neuroprotective tiv thaiv glutamate, beta amyloid pigmentation, thiab H2O2-induced toxicity.
Huperzine A tuaj yeem txhawb kev loj hlob ntawm hippocampal neural qia hlwb (NSCs). Zoo li txhawb kev loj hlob ntawm paj hlwb ntawm biorelated koob tshuaj.
