Hyaluronidase |37326-33-3
Khoom Specification:
Hyaluronidase yog ib qho enzyme uas muaj peev xwm hydrolyze hyaluronic acid (hyaluronic acid yog ib feem ntawm cov ntaub so ntswg matrix uas muaj cov nyhuv diffusion ntawm limiting dej thiab lwm yam extracellular tshuaj).
Nws tuaj yeem txo qis viscosity ntawm cov tshuaj intercellular ib ntus, txhawb cov subcutaneous infusion, hauv zos khaws cia exudate lossis ntshav kom nrawm nrawm thiab pab txhawb kev nqus, thiab yog ib qho tseem ceeb ntawm cov tshuaj dispersant.
Clinically siv los ua tshuaj permeation tus neeg sawv cev los txhawb kev nqus tshuaj, txhawb lub zos edema lossis hematoma dissipation tom qab phais thiab raug mob.
| Yam khoom | SPEC |
| Tus nqi PH | 5.0-8.5 Nws |
| Qhov Loj | 100% Txog 80 Mesh |
| Assay | 98% |
| Poob rau ziab | ≦5.0% |
| Kev ua si | Tsis tsawg tshaj 300(400-1000)IU / mg, ntawm cov khoom qhuav |
| Lub teeb transmittance | T550nm> 99.0% |
| Tag Nrho Phaj suav | ≤1000cfu / g |
| Total Poov & Pwm | ≤100cfu / g |
| Cia tej yam kev mob | 2-8 ° C |
Khoom Description
Product Description:
Dawb los yog lub teeb daj flocculent lyophilized tshuaj, tsw, yooj yim soluble nyob rau hauv dej, insoluble nyob rau hauv ethanol thiab acetone, nrog ib tug zoo pH tus nqi ntawm 4.5-6.0.
Kev ruaj ntseg: cov khoom khov-qhuav tsis muaj qhov txo qis hauv qhov tseem ceeb tom qab khaws cia ntawm 4 ℃ rau ib xyoos;
Nyob rau hauv cov xwm txheej ntawm 42 ℃, cov haujlwm tseem tsis hloov pauv tom qab cua sov rau 60 feeb;Thaum tshav kub kub ntawm 100 ℃ rau 5 feeb kom khaws 80% tseem ceeb;Tsawg concentration aqueous daws yog qhov ua rau tsis ua haujlwm, thiab ntxiv NaCl tuaj yeem ua rau lawv ruaj khov;Yooj yim rau deteriorate thaum raug tshav kub.
Inhibitors muaj xws li hnyav hlau ions (Cu2+, HR <2+, Fe<3+Chemalbook, Mn<2+, Zn<2+), acid organic dyes, bile ntsev, polyanions, thiab siab molecular hnyav polysaccharides xws li Chondroitin sulfate B, heparin, thiab heparan sulfate.
Lub activator yog polycation.Kev nqus coefficient ntawm 1% aqueous tov ntawm 280nm yog 8. Hyaluronidase feem ntau hydrolyzes N-acetyl hauv hyaluronic acid- β- Nruab nrab ntawm D-glucosamine thiab D-glucuronic acid β- 1,4-bond, tsim tetrasaccharide residues tsis muaj enzymes. Cov tshuaj tiv thaiv: hyaluronic acid + H2O oligosaccharides.
Daim ntawv thov:
1. Siv rau kev tshawb fawb biochemical
2. Clinically, nws yog feem ntau siv los txhawb lub dissipation ntawm lub zos edema los yog hematoma tom qab kev phais thiab kev raug mob, txo qhov mob ntawm qhov chaw txhaj tshuaj, thiab accelerate lub nqus ntawm subcutaneous thiab intramuscular txhaj tshuaj.
3. Nws kuj tseem siv tau rau cov hnyuv adhesions.
Pob: 1g, 5g, 10g, 30g, 50g, 100g, 500g, 1kg, 5kgs, 10kgs,25 kgs / hnab los yog raws li koj thov.
Cia:Khaws ntawm qhov chaw ventilated, qhuav.
Executive Standard:International Standard.